The Performance: 

On the one machine which doesn't seem to have the Lachesis pixel problems, the mouse performs beautifully in-game.  Prior to using the Lachesis, my rockets in TF2 would often hit close to where I intended them to go, but rarely on the mark.  With the Lachesis, my rockets are actually hitting where I'm aiming. Minor movement modifications can be made with a higher dpi mouse that would cause my 400 dpi mouse to jerk too far in a direction. I'm a bit floored as to the difference between my old mouse and these new ones.  I feel like all this time I've been handicapped and didn't know it.  The Lachesis proved to be slightly more sensitive than the DeathAdder, however both mice have improved my FPS games considerably over my old Microsoft IntelliMouse.  These mice are incredibly precise and smooth compared to a 400 dpi mouse.  Even when I play an isometric game like Mythos, I'm finding that I've gotten so used to that high dpi that I can't stand using anything else now.

Conclusion: 

Until they fix the skipping pixel problem for the Lachesis, I don't recommend purchasing this mouse.  Once they update their drivers and fix their bugs, I may change my mind as I do like the feel of this mouse a little better than the DeathAdder.

So is there a difference between 4000 and 1800 dpi?  For FPS gaming, I'd say a 4000 dpi mouse is not going to give you an edge over an 1800 dpi mouse.  There is a difference. The Lachesis is a little more sensitive, but it's not significant enough to win the day.  I like the Lachesis for it's feel and button placement, and I would use it over the DeathAdder if it's drivers weren't so frustratingly buggy.  In the meantime, the DeathAdder is certainly a good choice and one I would recommend.

Technical Specifications:

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